Plenhyage XL Thin 1x2ml represents the most delicate formulation in the Plenhyage Polynucleotide range, specifically designed for younger patients or those seeking preventive skin rejuvenation. This innovative injectable skin booster provides cellular regeneration, hydration, and elasticity enhancement by stimulating fibroblast activity and collage
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Plenhyage XL Thin 1x2ml represents the most delicate formulation in the Plenhyage Polynucleotide range, specifically designed for younger patients or those seeking preventive skin rejuvenation. This innovative injectable skin booster provides cellular regeneration, hydration, and elasticity enhancement by stimulating fibroblast activity and collagen synthesis at a biological level.
Developed by Regenyal Laboratories (Italy), a global leader in regenerative aesthetic medicine, Plenhyage XL Thin leverages the biorestructuring properties of highly purified polynucleotides (PN) — DNA fragments of natural origin that improve the skin’s metabolic processes and restore its physiological balance.
Unlike conventional hyaluronic acid injectables that simply hydrate, Plenhyage Thin acts as a regenerative stimulator, promoting the self-repair mechanisms of dermal tissue. It improves microcirculation, enhances oxygenation, and creates a more structured extracellular matrix — leading to a smoother, firmer, and visibly radiant complexion.
Mechanism of Action:
Once injected into the dermis, polynucleotides bind water molecules, delivering deep and sustained hydration. They also neutralize free radicals, reducing oxidative stress and inflammation. This creates a healthy microenvironment for fibroblast proliferation and tissue regeneration.
Over time, the treatment boosts the synthesis of new collagen (types I and III) and elastin fibers, improving both dermal thickness and elasticity.
Clinical Benefits:
Improves hydration and skin luminosity
Reduces fine lines and early wrinkles
Enhances elasticity and skin tone
Stimulates fibroblast activity for long-term collagen regeneration
Prevents early signs of aging and maintains youthful skin balance
Supports post-procedure skin recovery (e.g., after chemical peels, microneedling, or laser therapy)
This formulation is especially recommended for younger patients (25–40 years) or those with mild photoaging, providing gentle yet effective skin revitalization.
Clinical Protocol:
3–4 sessions, spaced 2–3 weeks apart
Maintenance every 6 months
Injectable using microinjections, papular, or retrograde threading techniques
Treatment Areas:
Face (including periorbital and perioral areas)
Neck
Décolletage
Hands
Areas with fine lines or loss of elasticity
Usage:
Administered by qualified medical professionals through microinjection or cannula technique.
Ideal as a standalone rejuvenating treatment or in combination with HA fillers, mesotherapy, microneedling, or chemical peels to enhance overall skin quality.
Recommended treatment plan:
Initial course of 3–4 sessions, every 2–3 weeks
Maintenance every 6–9 months, depending on skin condition
Ingredient List:
Polynucleotides (PN): 10 mg/ml – Purified DNA fragments that promote fibroblast activation, hydration, and tissue regeneration
Buffer Solution: Maintains physiological pH and osmolarity
Water for Injection: Provides sterility and biocompatibility
Product Dimensions / Size:
1 x 2ml prefilled syringe per box
Sterile and single-use
Needles not included
Product Duration:
Results are typically visible after the first session, with progressive improvement in texture, tone, and hydration. Duration of results: approximately 6–9 months, depending on individual skin condition and maintenance treatments.
Popular Questions & Answers
1. What is Plenhyage XL Thin used for?
Plenhyage XL Thin is designed for mild skin aging, dehydration, and loss of elasticity, offering preventive rejuvenation and hydration through polynucleotide stimulation.
2. Who is the ideal candidate for Plenhyage Thin?
Ideal for younger patients (25–40 years) or those showing early signs of skin aging, dullness, or fine lines who want to maintain firmness and glow.
3. How long do results last?
Results generally last 6–9 months, depending on the patient’s skin condition, treatment frequency, and maintenance care.
4. Can Plenhyage Thin be combined with other treatments?
Yes. It can be safely combined with HA fillers, microneedling, PRP, and mesotherapy to enhance skin texture and regenerative results.
5. How does Plenhyage Thin differ from Plenhyage Medium or Strong?
Plenhyage Thin has the lowest PN concentration (10 mg/ml), making it perfect for preventive treatments or delicate skin, whereas Medium and Strong target more advanced aging concerns.
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