Plenhyage Xl Medium

Plenhyage XL Medium 1 x 2ml is an advanced polynucleotide-based skin booster developed by Regenyal Laboratories, a pioneer in regenerative aesthetics. This biorestructuring injectable treatment targets the underlying causes of skin aging by stimulating cellular repair, collagen formation, and deep dermal hydration.

At its core, Plenhyage XL Medium contains high-purity polynucleotides (PN) — DNA fragments derived through a natural purification process that ensures biocompatibility and safety. Once injected, these polynucleotides act as scavengers of free radicals, creating an optimal environment for fibroblast proliferation and extracellular matrix regeneration.

Unlike traditional hyaluronic acid-based skin boosters, Plenhyage XL Medium offers long-term dermal restructuring rather than temporary hydration. It is ideal for patients with early signs of aging, mild atrophy, or post-acne scarring, delivering smoother, firmer, and more luminous skin.

Mechanism of Action:

• Fibroblast Activation: Polynucleotides stimulate fibroblast activity, promoting collagen and elastin synthesis for improved firmness.

• Hydration & Elasticity: PN molecules bind to water, increasing tissue hydration and enhancing elasticity.

• Antioxidant Protection: PN neutralizes free radicals and reduces oxidative stress in dermal tissues.

• Tissue Regeneration: Supports neocollagenesis and tissue remodeling, improving the skin’s microstructure.

Plenhyage XL Medium is resorbable, non-crosslinked, and bio-restructuring, making it a safe and natural approach to anti-aging and regenerative aesthetics. Treatments typically consist of 2–4 sessions spaced 2–3 weeks apart, with results visible after the first application and continuing to improve over time.

Key Benefits:

• Stimulates fibroblast proliferation and collagen synthesis

• Provides long-term tissue regeneration

• Improves skin tone, elasticity, and firmness

• Deeply hydrates and revitalizes dull, tired skin

• Reduces fine lines, wrinkles, and early photoaging

• Enhances skin structure post-procedure or post-acne

• Safe, biocompatible, and non-inflammatory

• CE-marked medical aesthetic device

Treatment Areas:

• Face (including perioral and periorbital areas)

• Neck

• Décolletage

• Hands

• Post-acne or scarred skin

• Mildly atrophic or photoaged skin

Usage:

Inject Plenhyage XL Medium into the mid to deep dermis using microinjection, linear, or retrograde threading technique.
Recommended protocol:

• 2–4 sessions, spaced 2–3 weeks apart

• Maintenance session every 3–6 months, depending on skin condition

Ingredient List:

• Polynucleotides (PN): 15 mg/ml – biotechnologically derived DNA fragments that stimulate fibroblast activity and promote cellular regeneration.

• Buffer Solution: Maintains physiological pH for safety and stability.

• Water for Injection: Sterile medium ensuring purity and smooth delivery.

Product Dimensions / Size:

• Volume: 1 x 2ml prefilled syringe

• Packaging: 1 sterile syringe per box

• Needles: Not included

Duration:

Results last 6–9 months, depending on the patient’s skin type, lifestyle, and treatment protocol.
 

Popular Questions & Answers

1. What is Plenhyage XL Medium used for?
Plenhyage XL Medium is a regenerative injectable that improves skin elasticity, hydration, and structure by stimulating fibroblast activity through polynucleotides.

2. How is Plenhyage XL Medium different from HA skin boosters?
Unlike hyaluronic acid, which offers temporary hydration, Plenhyage’s polynucleotides repair the dermis at a cellular level, promoting long-term regeneration and collagen renewal.

3. How many treatments are needed?
A full course typically consists of 2–4 sessions spaced 2–3 weeks apart, with maintenance every 6 months for optimal, sustained results.

4. Is it safe for all skin types?
Yes. Plenhyage is biocompatible, non-inflammatory, and CE-certified, making it safe for all skin types, including sensitive and post-procedure skin.

5. Can Plenhyage be combined with other aesthetic treatments?
Yes. It can be safely combined with chemical peels, microneedling, skin boosters, or hyaluronic acid fillers for enhanced rejuvenation results.